Notification from person discharging managerial responsibilities in the Company due to execution of the Stock Grant Program – Article 19 of MAR

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Achievement of the second milestone under license agreement with Exelixis Inc.

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Notification from a person discharging managerial responsibilities in the Company – Article 19 of MAR

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Dosing of the first patient in the RIVER-81 Phase II study of RVU120 in combination with venetoclax

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Registration of series K subscription warrants of the Company with the National Depository for Securities

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Publication dates for periodic reports in 2024

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Take-up of series K subscription warrants by the European Investment Bank

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Resignation of a member of the Company’s Supervisory Board from his position

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