AACR

October 23, 2024

AACR-NCI-EORTC International Conference (ENA) 2024, October 23-25, 2024

Year

2024

Target

CDK8, CDK19, ONCO Prime, RVU120 (CDK8/CDK19), Novel Targets, RVU 305 (PRMT5), WRN

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    Phase I/II trial of RVU120, a CDK8/CDK19 inhibitor in patients with relapsed/refractory metastatic or advanced solid tumors

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    Discovery of novel MTA-cooperative PRMT5 preclinical candidate as targeted therapeutics for MTAP-deleted cancers

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    Discovery of WRN inhibitors as targeted therapy in the treatment of microsatellite unstable (MSI-H) tumors

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    Exploring Synthetic Lethality and Novel Drug Combinations in Patient-Derived Cells

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