AACR
April 1, 2017
AACR Annual Meeting 2017, 1 - 5 April 2017, Washington, DC, USA
Year
2017
Target
GCN2, PIM/FLT3, SHMT, SMARCA
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"Development of small molecule selective inhibitors of GCN2 as an immunotherapy aimed at preventing immune escape of tumor cells"
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"Differential activity on lung adenocarcinoma cells with loss-of-function mutations of SWI/SNF protein SMARCA4"
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"Small molecule inhibitors of SHMT1/2 validate serine metabolism as a target in the treatment of c-Myc positive solid tumors"
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"Inhibition of CDK8 kinase with SEL120-34A allows for a personalized approach in AML"
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"Development of a potent, dual pan-PIM/FLT3 inhibitor for the treatment of heme malignancies"
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