AACR
23 czerwca 2020
AACR Virtual Annual Meeting II, June 22-24, 2020
Rok
2020
Cel
RVU120 (CDK8/CDK19), STING, HPK1, A2A/A2B, SMARCA
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"Synergistic effect of CDK8 and BCL-2 inhibition in AML through regulation of MCL-1 and BIM balance"
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"In vivo and in vitro characterization of RVU330 best-in-class dual A2A/A2B adenosine receptor antagonist"
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"Development of selective small molecule STING agonists suitable for systemic administration"
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"Development and characterization of small molecule HPK1 inhibitors"
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"Development of novel, selective SMARCA2 (BRM) degraders for treatment of SMARCA4 (BRG1) mutated tumors"
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