AACR

1 kwietnia 2017

AACR Annual Meeting 2017, 1 - 5 April 2017, Washington, DC, USA

Rok

2017

Cel

RVU120 (CDK8/CDK19), daposertib (MEN1703 / SEL24), GCN2, PIM/FLT3, SHMT, SMARCA

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  • plik pdf

    "Development of small molecule selective inhibitors of GCN2 as an immunotherapy aimed at preventing immune escape of tumor cells"

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    "Differential activity on lung adenocarcinoma cells with loss-of-function mutations of SWI/SNF protein SMARCA4"

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  • plik pdf

    "Small molecule inhibitors of SHMT1/2 validate serine metabolism as a target in the treatment of c-Myc positive solid tumors"

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  • plik pdf

    "Inhibition of CDK8 kinase with SEL120-34A allows for a personalized approach in AML"

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  • plik pdf

    "Development of a potent, dual pan-PIM/FLT3 inhibitor for the treatment of heme malignancies"

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